Coluracetam is a nootropic supplement that has the ability to sharpen memory and focus. It is also known for its mood enhancing properties. It can also help with depression and anxiety. It has also been shown to improve vision.
This nootropic was first developed by Mitsubishi Tanabe Pharma Corporation as a potential Alzheimer’s treatment. It was later licensed to BrainCells Inc.
Memory Enhancement
Coluracetam is a fat-soluble nootropic in the racetam family of drugs. It boosts cognitive functions and improves memory. It also enhances vision and has anxiolytic qualities. This nootropic acts as a choline uptake enhancer and increases high-affinity choline uptake (HACU). This process helps increase the production of the neurotransmitter acetylcholine, which is important for memory. It can be used alone or stacked with other nootropics.
It also improves AMPA receptor potentiation and boosts glutamate neurotransmission. This results in improved learning and memory, as well as better focus and attention. It is a great supplement for those suffering from Alzheimer’s disease, or other forms of dementia.
Additionally, this drug has been shown to enhance pattern recognition memory and mental digit span. It also has anxiolytic effects and can help alleviate anxiety. For best results, take Coluracetam powder europe with a choline source like Alpha GPC or CDP Choline. This stack has been shown to provide enhanced memory and cognition with a faster onset and longer duration than coluracetam alone.
Anxiety Relief
Like most nootropics, coluracetam can help relieve anxiety. It does so by enhancing memory and improving concentration and alertness. It also increases mood and reduces stress. The anxiolytic effects of this racetam can be attributed to its ability to increase acetylcholine and desensitize AMPA receptors.
Originally developed by Mitsubishi Tanabe Pharmaceutical Corporation for Alzheimer’s disease, it was then transferred to Brain Cells Inc who conducted testing that showed it may have some potential in helping people with major depressive disorder and general anxiety. These trials reached phase 2a clinical trials but were never published, and the company closed down in 2014.
Today, this racetam is most commonly used as a dietary supplement to improve mood, focus, memory and learning abilities. It is a fat-soluble compound so eating it with a meal high in healthy fats can aid absorption. It is known to boost vision through enhanced colors, intensified contrast, and brighter lights and can encourage the growth of new nerves for those suffering from retinal damage.
Vision Enhancement
Coluracetam benefits include boosting vision by encouraging the growth of nerves in the retina. It can also improve the condition of people with schizophrenia by growing acetylcholine which is usually impaired in this disorder. It can even boost color vision and shape recognition. Moreover, it can help those with Alzheimer’s disease by increasing acetylcholine levels and improving learning.
It is also thought to increase AMPA potentiation which can improve alertness. Moreover, it can improve mood disorders without affecting serotonin levels. Therefore, it is a good alternative to popular SSRIs which come with a number of detrimental side effects.
Coluracetam powder can be stacked with other nootropics to enhance its effects. It is recommended to take it with choline which can be found in supplements like Alpha GPC and citicoline. This will help in intensifying its effects and avoiding any headaches which can accompany it. It is also safe to stack it with cholinergic drugs such as NMDA receptor modulators.
Neurogenesis
Coluracetam is a nootropic that increases acetylcholine, a neurotransmitter that is crucial for memory formation and recall. It improves high-affinity choline uptake, the rate-limiting step in acetylcholine synthesis. It also acts as an AMPA receptor potentiator, making it a good choice for improving mood disorders without causing SSRI-like side effects.
Piracetam is the first racetam to hit the nootropics scene, and it works by boosting acetylcholine through its cyclic derivative structure. However, it does so by helping ACh receptors accept acetylcholine. Coluracetam does so by affecting the high-affinity choline uptake (HACU) process, and its only other comparable cousin is pramiracetam.
This is important because HACU impairment is a known risk factor for Alzheimer’s Disease and dementia. It’s also associated with low acetylcholine levels, which can cause brain fog and slow learning. Increasing choline uptake helps prevent these problems, and can even reverse some of the symptoms of Alzheimer’s disease. (3)